Russian forces hit Kharkiv with S-300 long-range missiles on Thursday night, the AFP news agency reported.
The city's Kholodnohirs'kyi and Shevchenkivskyi districts were hit hardest, with one person injured and treated at the scene, according to The Kyiv Independent.
Russian forces struck six times, said the head of the regional military administration, Oleg Synegubov.
Ukraine's northeastern Kharkiv region has been a constant target of Russian strikes, with one attack in October killing 51 people, according to news outlets.
Earlier on Thursday, Russian troops hit a coal mine in Ukraine's eastern city of Toretsk, injuring one person and causing significant damage, the AFP reported.
US military aid to Ukraine in danger due to opposition in Congress: White House
Meanwhile, America's National Security Council spokesman John Kirby said that the White House could not guarantee continued support for Ukraine beyond "a few more weeks," due to opposition from Republican lawmakers.
In October, US President Joe Biden asked Congress for a USD 106 billion national security package, including USD 61 billion in military assistance for Ukraine, according to reports at the time.
The proposal has stalled on Capitol Hill amid growing opposition within the Republican Party to providing further assistance for Kyiv, the PAP news agency reported.
Kirby told reporters on Thursday that the president was willing to strike a compromise with the Republicans on border policy, in order to reach a breakthrough on funding for Ukraine's fight against the Russian invasion, the PAP news agency reported.
Russia invaded Ukraine on February 24, 2022, launching the largest military campaign in Europe since World War II.
Friday is day 653 of Russia's war on Ukraine.
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Source: AFP, The Kyiv Independent, PAP, The Hill, C-SPAN